[Source: US National Library of Medicine, full page: (LINK). Abstract, edited.]
Arch Virol. 2014 Jun 7. [Epub ahead of print]
Low infectivity of a novel avian-origin H7N9 influenza virus in pigs.
Yum J1, Park EH, Ku KB, Kim JA, Oh SK, Kim HS, Seo SH.
Author information: 1Laboratory of Influenza Research, College of Veterinary Medicine, Institute for Influenza Virus, Chungnam National University, 220 Gung Dong, Yuseong Gu, Daejeon, 305-764, Republic of Korea.
We studied the pathogenesis and transmissibility of a novel avian-origin H7N9 influenza virus in pigs. When pigs were infected with H7N9 influenza virus, they did not show any clear clinical signs (such as sneezing, fever and loss of body weight), and they shed viruses through their noses for 2 days after infection. No transmission occurred between infected and naïve pigs. Pigs suffered from mild pneumonia, which was accompanied by the induction of inflammatory cytokines and chemokines such as IL-8 and CCL1. Taken together, our results suggest that pigs may not play an active role in transmitting H7N9 influenza virus to mammals.
PMID: 24906526 [PubMed - as supplied by publisher]